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Solid Phase Extraction (SPE)

The Solid Phase Extraction (SPE) solutions from Biotage provide reliable, efficient, and reproducible sample preparation for a wide range of analytical applications. With a comprehensive portfolio of SPE cartridges, disks, and accessories, these products are designed to handle complex matrices such as biological fluids, water, food, and environmental samples. Offering multiple retention mechanisms including non-polar, polar, ion-exchange, mixed-mode, and specialty phases, Biotage SPE products ensure high recovery, selectivity, and purity in pharmaceutical, environmental, food safety, and forensic analysis.

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Features
  • Broad portfolio of SPE solutions: cartridges, disks, plates, and accessories
  • Multiple retention mechanisms: non-polar, polar, ion exchange, mixed-mode, specialty phases
  • High reproducibility and recovery across a wide range of analytes
  • Ready-to-use SPE disks for fast and convenient workflows
  • Options for manual, semi-automated, and fully automated sample preparation
  • Compatible with biological fluids, water samples, food extracts, and complex matrices
Applications
  • Pharmaceutical & Biotech – Drug analysis, metabolite extraction, bioanalysis of therapeutic oligonucleotides
  • Environmental Testing – Pesticides, pollutants, SVOCs, oil and grease in water samples
  • Food & Beverage – Residue analysis, contaminant detection
  • Forensic & Toxicology – Drug screening, toxic compound isolation
  • Analytical Laboratories – Automated sample preparation workflows
Specifications
Product Retention Mechanism / Application Key Use Case
ISOLUTE Mixed-Mode SPE Dual mixed-mode (acidic or basic analytes from biological fluids) Robust extraction with dual retention
ISOLUTE Non-Polar SPE Hydrophobic (non-polar) Extraction from aqueous matrices
ISOLUTE Polar SPE Polar retention Extraction from non-polar matrices
ISOLUTE Ion Exchange SPE Selective ion exchange Acidic or basic analytes from aqueous matrices
Oligo SPE SPE for therapeutic oligonucleotides Bioanalysis of therapeutic oligos
ISOLUTE Specialty SPE Application-specific Tailored extractions for niche needs
On-line SPE Cartridges Automated workflows Integration into LC/MS systems
SPE Disks High-performance SVOC extraction Water sample testing
Ready SPE Disks Pre-assembled disposable holders Fast, convenient SVOC water extraction
Oil & Grease SPE Disks Hexane Extractable Material (HEM) Oil & grease recovery in dirty water
ISOLUTE Accessories Tubes, frits, caps, stopcocks, adapters Support for SPE workflows
ISOLUTE Collection Plates High purity, solvent resistant Efficient collection of SPE eluates